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You are here:Home » Antibodies » Abs to Myelin » Anti -MOG (Myelin-oligodendrocyte Glycoprotein)

Anti -MOG (Myelin-oligodendrocyte Glycoprotein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IP IH FC
Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). MOG protein constitutes only 0.01-0.5% of the CNS myelin proteins, has a mass of 27kD, and is located in the outermost layer of myelin sheath. Mouse MOG is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Auto- antibody response to mouse MOG has been observed in induced experimental autoimmune encephalomyelitis (EAE) in C57/BL6, 129/Sv, B6, and SJL mice.
Catalog #M9758-08S
ApplicationsSuitable for use in Immunoprecipitation, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunoprecipitation: 2-5ug/10e7 cell extract
Western Blot: 1:1000
Immunohistochemistry: 1:50-1:200
Flow Cytometry: 1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoB1A
HostMouse
ConcentrationNot determined
FormSupplied as a liquid in in 40mM MOPS, pH7.5, 50% glycerol, 0.1% sodium azide, 0.1% BSA.
PurityPurified
ImmunogenRecombinant corresponding to myelin oligodendrocyte glycoprotein.
SpecificityRecognizes MOG. Species Crossreactivity: mouse, human and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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