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Anti -MOG (Myelin-oligodendrocyte Glycoprotein)
Anti -MOG (Myelin-oligodendrocyte Glycoprotein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IP IH FC |
|
| Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). MOG protein constitutes only 0.01-0.5% of the CNS myelin proteins, has a mass of 27kD, and is located in the outermost layer of myelin sheath. Mouse MOG is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Auto- antibody response to mouse MOG has been observed in induced experimental autoimmune encephalomyelitis (EAE) in C57/BL6, 129/Sv, B6, and SJL mice. | | | Catalog # | M9758-08S | | Applications | Suitable for use in Immunoprecipitation, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunoprecipitation: 2-5ug/10e7 cell extract | | Western Blot: 1:1000 | | Immunohistochemistry: 1:50-1:200 | | Flow Cytometry: 1:200 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | B1A | | Host | Mouse | | Concentration | As reported | | Form | Supplied as a liquid in in 40mM MOPS, pH7.5, 50% glycerol, 0.1% sodium azide, 0.1% BSA. | | Purity | Purified | | Immunogen | Recombinant corresponding to myelin oligodendrocyte glycoprotein. | | Specificity | Recognizes MOG. Species Crossreactivity: mouse, human and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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