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You are here:Home » Antibodies » Abs to Enzymes, Myeloperoxidase » Anti -Myeloperoxidase (MPO)

Anti -Myeloperoxidase (MPO)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Myeloperoxidase is a lysosomal enzyme found in myeloid cells that metabolize most of the hydrogen peroxide generated by activated phagocytes. It is in all myeloid cells including mature granulocytes, neutrophil granulocytes and monocyterin blood in precursors of granulocytes in the bone marrow and in Kupffer cells of the liver. Myeloperoxidase antibodies are superior markers to myeloperoxidase mRNA whose levels decrease with cell maturation and are not detectable from the myelocyte stage onwards. This antibody will be helpful in identifying tissues of myeloid origin.
Catalog #M9760-01T
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:75-1:150 for 1 hr at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Tonsil (cytoplasmic staining pattern)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No59A5
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenRecombinant protein representing 101aa from exon 7 of the human myeloperoxidase molecule.
SpecificityRecognizes human Myeloperoxidase.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=1.11.2.2


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