Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Myosin » Anti -MyoGEF, NT (Myosin-interacting Guanine Nucleotide Exchange Factor, FLJ10665, MGC126315, MGC126353, MGC126354, Pleckstrin Homology Domain-containing Family G Member 6, PH Domain-containing Family G Member 6, PLEKHG6)

Anti -MyoGEF, NT (Myosin-interacting Guanine Nucleotide Exchange Factor, FLJ10665,
MGC126315, MGC126353, MGC126354, Pleckstrin Homology Domain-containing Family G Member 6,
PH Domain-containing Family G Member 6, PLEKHG6)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It Also activates RHOG and does not activate RAC1, or to a much lower extent than RHOA and RHOG. Its part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, It is required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, it is required for normal macropinocytosis.
Catalog #M9789-85
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human MyoGEF (KLH).
SpecificityRecognizes human MyoGEF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPleckstrin Homology Domain Containing, Family G (with RhoGef Domain) Member 6


External Links