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You are here:Home » Molecular Biology » MB-Serum Proteins » Myoglobin, Cardiac, Rabbit (MB)

Myoglobin, Cardiac, Rabbit (MB)

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Specifications

Myoglobin, an intracellular haemoprotein expressed in the heart and oxidative skeletal myofibres of vertebrates, binds molecular oxygen and may facilitate oxygen transport from erythrocytes to mitochondria, thereby maintaining cellular respiration during periods of high physiological demand. Myoglobin may serve a variety of functions in muscular oxygen supply, such as oxygen storage, facilitated O(2) diffusion, and myoglobin-mediated oxidative phosphorylation. Disruption of myoglobin results in the activation of multiple compensatory mechanisms that steepen the pO(2) gradient and reduce the diffusion path length for O(2) between capillary and the mitochondria.
Catalog #M9800-45
SourceRabbit cardiac tissue
Molecular Weight~17kD
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~17kD
SourceRabbit cardiac tissue
Purity~95% (SDS-PAGE). Purified by Ion Exchange chromatography.
ConcentrationAs reported
FormSupplied as a liquid in 5mM sodium phosphate, 75mM sodium chloride, pH7.2, 50% glycerol, 0.05% sodium azide.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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