Anti -Myosin VIIa (Myosin 7a, Myo7a, MYOVIIA, Deafness Autosomal Dominant 11, DFNA11,
Deafness Autosomal Recessive 2, DFNB2, MYU7A, NSRD2, Usher Syndrome 1B, Ush1B)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
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| Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions. | | | Catalog # | M9848-03H | | Positive Control | Western Blot: mouse testes lysate. Immunohistochemistry: Paraffin. mouse ear | | Applications | Suitable for use in Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~1mg/ml | | Form | PBS, 1 mg/ml BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: S(16)GQEFDVPIGAVVKLC(31). Immunizing peptide corresponds to amino acid residues 16-31 from mouse myosin VIIa. This sequence is completely conserved in mouse, porcine, and human myosin VIIa. | | Specificity | Detects Myosin VIIa from mouse tissues as well as recombinant protein. Species Crossreactivity: Expected to crossreact with Human and porcine due to sequence homology (100%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Myosin VIIa (Myosin 7a, Myo7a, MYOVIIA, Deafness Autosomal Dominant 11, DFNA11, Deafness Autosomal Recessive 2, DFNB2, MYU7A, NSRD2, Usher Syndrome 1B, Ush1B) |
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