Anti -Myosin IIA, Non-muscle (Cellular Myosin Heavy Chain Type A, DFNA17, EPSTS, FTNS, MGC104539, MHA, MYH2A, MYH9, MYHas8, MyHC-2A, MyHC-IIa, MYHSA2, Myosin 9, Myosin Heavy Chain 9, Myosin Heavy Chain 9 Non-muscle, Myosin Heavy Chain Non-muscle IIa, Myosin Hea
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IC IF |
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| Myosin heavy chain type A is a critical component of the cellular contractile apparatus. It is involved in maintaining cell-cell adhesion in early mammalian embryos and ablation of this protein leads to prenatal lethality. Mutation in the human MYH9 gene lead to MYH9-related hereditary macrothrombocytopenia (HMTC) characterized by a reduced number of blood platelets. | | | Catalog # | M9848-12 | | Applications | Suitable for use in Western Blot, Immunofluorescence, Immunocytochemistry and Immunoprecipitation. Other applications not tested. | | Recommended Dilutions | Immunocytochemistry/Immunofluorescence: 1:100 | | Western Blot: 1:1000. Detects a band at ~200kD. Staining of myosin IIA (nonmuscle) is inhibited by the immunizing peptide. Additional bands may be detected in some preparations. | | Optimal dilutions to be determined by the researcher. | | Positive Control | MDCK or Jurkat whole cell extract (Western Blot). NRK cells (Immunofluorescence). | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 0.01M PBS, pH 7.4, 1% BSA, 15mM sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1950-1961 of human non-muscle Myosin IIA, conjugated to KLH. Cellular Localization: Cytoplasmic. | | Specificity | Recognizes human myosin IIA. Species Crossreactivity: rat and canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Myosin IIA, Non-muscle (Cellular Myosin Heavy Chain Type A, DFNA17, EPSTS, FTNS, MGC104539, MHA, MYH2A, MYH9, MYHas8, MyHC-2A, MyHC-IIa, MYHSA2, Myosin 9, Myosin Heavy Chain 9, Myosin Heavy Chain 9 Non-muscle, Myosin Heavy Chain Non-muscle IIa, Myosin Hea |
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