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You are here:Home » Antibodies » Antibodies-Myosin » Anti -Myosin (Cardiac) Light Chain (MLC-I, Essential Myosin Light Chain Isoform)

Anti -Myosin (Cardiac) Light Chain (MLC-I, Essential Myosin Light Chain Isoform)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Human ventricular myosin light chain (MLC-I, Essential Myosin Light Chain Isoform) is a 21kD cardiac contractile protein, which is one of component of myosin structure. The protein MLC-I is present in the contractile apparatus and not in cytosol. In severe congestive heart failure (CHF), myofibrils may degenerate and subsequently, the myofibrillar components may be released into the circulation. The increased blood levels of MLC-I could indicate morphological changes in CHF, myocardial infarction, structural abnormalities in viable myocytes also observed in non-ischaemic CHF, myocardial necrosis.
Catalog #M9850-02A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a lyophilized powder from PBS, pH 7.2. Preservative free. Reconstitute with 50ul sterile ddH2O.
PurityPurified by immunoaffinity chromatography
ImmunogenRecombinant human myosin (cardiac) light chain fragment.
SpecificityRecognizes human mysosin (cardiac) light chain. The recombinant human myosin (cardiac) light chain fragment is homologous with the human serum myosin (cardiac) light chain fragment.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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