You are here:Home
»
Antibodies
»
Abs to Myosin
»
Anti -Myosin, Smooth Muscle, Heavy Chain 2 (MHC-2)
Anti -Myosin, Smooth Muscle, Heavy Chain 2 (MHC-2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Highly Purified |
B IH IF |
|
| The heavy chain of myosin II found in vertebrate smooth muscle is a non-striated muscle present in the walls of hollow organs, the vasculature, the respiratory and gastrointestinal tracts, uterus, bladder and eye. | | | Catalog # | M9850-12C | | The structure of myosin II is fundamentally the same in all muscle types and consists of two heavy chains, each bound by 2 distinct, essential and regulatory light chains. The globular motor domain located at the N-terminal domain of the heavy chains, catalyzes ATP hydrolysis and interacts with actin, whilst the heptad repeat sequences of the heavy chain tail domains promote dimerization, forming an alpha-helical coiled coil at the C-terminal domain. | | Applications | Suitable for use in Immunofluorescence, Immunohistochemistry (frozen), and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:150 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Bovine | | Concentration | As reported | | Form | Supplied as a liquid in 20mM TRIS, pH 7.5, 150mM sodium chloride, 0.006% sodium azide. | | Purity | Purified by Ion Exchange chromatography. | | Immunogen | Bovine tracheal smooth muscle myosin. | | Specificity | Recognizes the heavy chain of myosin II found in vertebrate smooth muscle. Does not crossreact with myosin of skeletal or non-muscle origin. Species Crossreactivity: vertebrates. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
