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Specifications

Myriocin is an a-amino fatty acid derived from species of several genera of fungi, notably Myriococcum, Melanconis and Isaria. Myriocin is a potent inhibitor of sphingosine biosynthesis by blocking the first enzyme in the pathway, serine palmitoyltransferase. Myriocin induces apoptosis by depletion of cellular sphingolipids, inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant.
Catalog #	M9931-20
Source	Mycelia sterilia (fungus)
Apperance	Off-white to grey powder
Solubility	Slightly soluble in DMSO, alcohols.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	35891-70-4
Molecular Formula	C21H39NO6
Molecular Weight	401.5
Source	Mycelia sterilia
Purity	~97%
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.