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You are here:Home » Biochemicals » Biochem-Antibiotics » Myriocin (Thermozymocidin, ISP)

Myriocin (Thermozymocidin, ISP)


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Myriocin is an a-amino fatty acid derived from species of several genera of fungi, notably Myriococcum, Melanconis and Isaria. Myriocin is a potent inhibitor of sphingosine biosynthesis by blocking the first enzyme in the pathway, serine palmitoyltransferase. Myriocin induces apoptosis by depletion of cellular sphingolipids, inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant.
Catalog #M9931-20
Source Mycelia sterilia (fungus)
Apperance Off-white to grey powder
Solubility Slightly soluble in DMSO, alcohols.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number35891-70-4
Molecular FormulaC21H39NO6
Molecular Weight401.5
SourceMycelia sterilia
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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