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You are here:Home » Antibodies » Abs to Myosin » Anti -MYRIP (SLAC2C, OTTHUMP00000209206, MGC130035, MGC130034, FLJ44025, synaptotagmin-like protein homologue lacking C2 domains-c, Slp homologue lacking C2 domains, rab effector MYRIP, DKFZp586F1018, exophilin 8, exophilin, SLAC2-C, MyRIP, myosin VIIA and Rab

Anti -MYRIP (SLAC2C, OTTHUMP00000209206, MGC130035, MGC130034, FLJ44025,
synaptotagmin-like protein homologue lacking C2 domains-c, Slp homologue lacking C2
domains, rab effector MYRIP, DKFZp586F1018, exophilin 8, exophilin, SLAC2-C, MyRIP, myosin
VIIA and Rab

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice.
Catalog #M9931-25A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:64000
Western Blot: 0.3-1ug/ml. ~90kD band observed in human brain amygdala lysates (calculated MW of 95.7kDaaccording to NP_056275.2).
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified from goat serum by ammonium sulfate precipitation followed by antigen affinity chromatography using the immunizing peptide.
ImmunogenSynthetic peptide corresponding to C-KDLMEPALESAVMY from the C Terminus of human MYRIP (NP_056275.2).
SpecificityRecognizes human MYRIP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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