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You are here:Home » Antibodies » Abs to Inflammasomes » Anti -NALP3, CT (NACHT, LRR and PYD Domains Containing Protein 3, NLR Family Pyrin Domain Containing 3, NLRP3, AGTAVPRL, AII, AII/AVP, AVP, Angiotensin/vasopressin Receptor AII/AVP-like, C1orf7, Caterpiller Protein 1.1, CLR1.1, Cold Autoinflammatory Syndrome 1

Anti -NALP3, CT (NACHT, LRR and PYD Domains Containing Protein 3, NLR Family Pyrin Domain
Containing 3, NLRP3, AGTAVPRL, AII, AII/AVP, AVP, Angiotensin/vasopressin Receptor
AII/AVP-like, C1orf7, Caterpiller Protein 1.1, CLR1.1, Cold Autoinflammatory Syndrome 1

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
Catalog #N0018-64H-PE
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human NLRP3 (KLH).
SpecificityRecognizes human NLRP3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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