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You are here:Home » Antibodies » Abs to Inflammasomes » Anti -NALP8 (NACHT, LRR and PYD Domains-containing Protein 8, Nucleotide-binding Oligomerization Domain Protein 16, PYRIN and NACHT-containing Protein 4, NLRP8, NOD16, PAN4)

Anti -NALP8 (NACHT, LRR and PYD Domains-containing Protein 8, Nucleotide-binding
Oligomerization Domain Protein 16, PYRIN and NACHT-containing Protein 4, NLRP8, NOD16,
PAN4)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
NALP8, like other NALP proteins, is a cytoplasmic protein that forms a subfamily within the larger CATERPILLER protein family. NALP8 is a short NALP, with an N-terminal pyrin (MEFV) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. Though the exact function of NALP8 is yet unknown reports suggest that it may be involved in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
Catalog #N0018-69A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa130-147 PEDLNVGETQVNLEEGES of human NALP8.
SpecificityRecognizes human NALP8. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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