Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Homeobox (HOX) » Anti -Nanog, phosphorylated (Ser71) (Homeobox Transcription Factor Nanog, Homeobox Protein NANOG, hNanog)

Anti -Nanog, phosphorylated (Ser71) (Homeobox Transcription Factor Nanog, Homeobox Protein
NANOG, hNanog)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E Gel
NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
Catalog #N0019-01M
ApplicationsSuitable for use in ELISA and Dot Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Dot Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to amino acid residues surrounding Ser71 of human NANOG (KLH).
SpecificityRecognizes human NANOG when phosphorylated at Ser71.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links