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You are here:Home » Antibodies » Abs to Homeobox (HOX) » Anti -Nanog (Embryonic Stem Cell Specific Homeobox Protein, FLJ12581, FLJ40451, hNanog, Homeobox Protein NANOG, Homeobox Transcription Factor Nanog, Nanog Homeobox)

Anti -Nanog (Embryonic Stem Cell Specific Homeobox Protein, FLJ12581, FLJ40451, hNanog,
Homeobox Protein NANOG, Homeobox Transcription Factor Nanog, Nanog Homeobox)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
NANOG is a transcription regulator involved with inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extra-embryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor by optimally binding to the DNA consensus sequence :5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
Catalog #N0019-01T
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
ELISA: 0.25ug/ml
Western Blot: 0.5-2.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipation.
ImmunogenRabbits immunized with a his fusion recombinant protein of human FOXP3
SpecificityRecognizes human Nanog.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEarly Embryo Specific Expression NK Family Gene, ENK


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