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You are here:Home » Antibodies » Abs to Nuclear Proteins » Anti -NCK Interacting Protein with SH3 Domain (NCKIPSD, AF3P21, MGC23891, SPIN90, WASLBP, WISH)

Anti -NCK Interacting Protein with SH3 Domain (NCKIPSD, AF3P21, MGC23891, SPIN90, WASLBP,
WISH)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
Catalog #N0550-80
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8C228
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenPartial sequence of recombinant full-length protein to human NCK Interacting Protein with SH3 Domain
SpecificityRecognizes human NCK Interacting Protein with SH3 Domain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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