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You are here:Home » Antibodies » Abs to Retinoblastoma Proteins » Anti -NDC80 Homolog, Kinetochore Complex Component (HEC, HEC1, Highly Expressed in Cancer, Highly Expressed in Cancer Rich in Leucine Heptad Repeats, HsHec1, hsNDC80, Kinetochore Associated 2, KNTC2, Kinetochore Protein Hec1, NDC80, Retinoblastoma Associated Pr

Anti -NDC80 Homolog, Kinetochore Complex Component (HEC, HEC1, Highly Expressed in Cancer,
Highly Expressed in Cancer Rich in Leucine Heptad Repeats, HsHec1, hsNDC80, Kinetochore
Associated 2, KNTC2, Kinetochore Protein Hec1, NDC80, Retinoblastoma Associated Pr

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
Catalog #N0570-12B
ApplicationsSuitable for use in ELISA (peptide) and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: YEKKATLIKSSEE representing the C-Terminus of the human protein (residues 630-642), according to NP_006092.
SpecificitySpecies Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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