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You are here:Home » Antibodies » Abs to Retinoblastoma Proteins » Anti -NDC80 Homolog, Kinetochore Complex Component (Highly Expressed in Cancer, HEC, HEC1, HsHec1, hsNDC80, Kinetochore Associated 2, KNTC2, Kinetochore Protein Hec1, Kinetochore Protein NDC80 Homolog, NDC80, Retinoblastoma Associated Protein HEC, TID3, NDC80 H

Anti -NDC80 Homolog, Kinetochore Complex Component (Highly Expressed in Cancer, HEC, HEC1,
HsHec1, hsNDC80, Kinetochore Associated 2, KNTC2, Kinetochore Protein Hec1, Kinetochore
Protein NDC80 Homolog, NDC80, Retinoblastoma Associated Protein HEC, TID3, NDC80 H

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM]
Catalog #N0570-12F
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C462
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa545-642 of human KNTC2.
SpecificityRecognizes human KNTC2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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