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Anti -Netrin G1 Ligand Precursor (NGL-1, LRRC4C, leucine rich repeat containing 4C KIAA1580, UNQ292, PRO331) (Biotin)
Anti -Netrin G1 Ligand Precursor (NGL-1, LRRC4C, leucine rich repeat containing 4C KIAA1580, UNQ292, PRO331) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
B |
|
| The Netrin-G1 ligand (NGL-1) promotes the outgrowth of thalamocortical axons. Human netrin G1 ligand is a transmembrane protein containing leucine-rich repeat (LRR) and immunoglobulin (Ig) domains that specifically interacts with netrin-G1 through its LRR region. Postsynaptic netrin-G ligand (NGL) CAMs associate with netrin-G CAMs in an isoform-specific manner and, through their cytosolic tail, with the abundant postsynaptic scaffold postsynaptic density-95 (PSD-95). | | | Catalog # | N1193-10M | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Westerm Blot: 0.1-0.2ug/ml with the appropriate secondary reagents to detect human NGL-1. The detection limit for rhNGL-1 is approximately 2ng/lane under non-reducing and reducing | | conditions. Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | ~50ug/ml | | Form | Supplied as lyophilized from a 0.2um sterile-filtered solution in PBS, 50ug BSA. Reconstitute with sterile Tris-buffered saline pH 7.3 (20mM Tris base,150mM NaCl), 0.1% BSA. If 1ml of buffer is used, the antibody concentration will be 50ug/ml. | | Purity | Purified by immunoaffinity chromatography. | | | Immunogen | Purified, NS0-derived, recombinant human NGL-1 extracellular domain (rhNGL-1) | | Specificity | Recognizes human NGL-1, extracellular domain. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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