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You are here:Home » Antibodies » Abs to Neuroligins » Anti -Neuroligin 1 (NLGN1)

Anti -Neuroligin 1 (NLGN1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
Catalog #N1260-01B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 0.5ug/ml detects Neuroligin-1 on 10ug of rat brain membrane tissue lysate.
Immunohistochemistry (paraffin): 1:300 detects Neuroligin-1 in rat adult brain tissue.
Optimal dilutions to be determined by the researcher.
Positive ControlRat brain membrane tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1k
Clone No11C248
HostMouse
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to rat Neuroligin-1.
SpecificityRecognizes rat Neuroligin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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