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You are here:Home » Antibodies » Abs to Neuroligins » Anti -Neuroligin 3 (NLGN3)

Anti -Neuroligin 3 (NLGN3)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
Catalog #N1260-03C
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1ug/ml detects Neuroligin-3 on 10ug of rat brain membrane tissue lysate.
Immunohistochemistry (paraffin): 1:400 detects Neuroligin-3 in rat brain (putamen area) and rat cerebellum tissue.
Optimal dilutions to be determined by the researcher.
Positive ControlRat brain membrane tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1k
Clone No11C249
HostMouse
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to rat Neuroligin-3 at the cytoplasmic domain.
SpecificityRecognizes rat Neuroligin-3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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