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You are here:Home » Antibodies » Abs to Enzymes, Glycosidase » Anti -NEU1, NT (Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal Sialidase, N-acetyl-alpha-neuraminidase 1, NANH)

Anti -NEU1, NT (Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal
Sialidase, N-acetyl-alpha-neuraminidase 1, NANH)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH IF
NEU encodes the lysosomal enzyme neuraminidase, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, neuraminidase is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in NEU that interfere with neuraminidase enzymatic activity can lead to sialidosis.
Catalog #N2090-01
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:500
Western Blot: 1:500
Immunohistochemistry (Formalin fixed paraffin embedded): 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
PuritySerum
ImmunogenFusion protein excluding the signal peptide (first 45aa) and the first 6 N-terminal aa of the processed form of human lysosomal neuraminidase, bacterially expressed.
SpecificityRecognizes human Sialidase 1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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