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You are here:Home » Antibodies » Abs to Nuclear Proteins » Anti -NFBD1 (Nuclear Factor with BRCT Domains Protein 1, MDC1, KIAA0170)

Anti -NFBD1 (Nuclear Factor with BRCT Domains Protein 1, MDC1, KIAA0170)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B
NFBD1, nuclear factor with BRCT domains protein 1, participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) superfamily of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence. A more recent renaming of NFBD1 is MDC1 (mediator of DNA damage checkpoint protein).
Catalog #N2159-25
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:200-1:1000
observed size: ~220 kD
positive control: Jurkat whole cell lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to amino acids 871-888 of human NFBD1.
SpecificityRecognizes human NFBD1 (Nuclear Factor with BRCT Domains Protein 1, MDC1, KIAA0170)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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