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You are here:Home » Antibodies » Abs to Neurofilament » Anti -Neuro lament L, 68kD (Neurofilament Light Polypeptide, NEFL, NFL, NF-L, 68kD Neurofilament Protein, NF68, CMT1F, CMT2E, FLJ53642, Neurofilament Triplet L Protein)

Anti -Neuro lament L, 68kD (Neurofilament Light Polypeptide, NEFL, NFL, NF-L, 68kD
Neurofilament Protein, NF68, CMT1F, CMT2E, FLJ53642, Neurofilament Triplet L Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
NEFL is type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. This protein comprises the axoskeleton and it functionally maintains the neuronal caliber. The protein may also play a role in intracellular transport to axons and dendrites. Mutations in this protein cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies.
Catalog #N2160-01D4
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide corresponding to aa177-207 from the center region of human Neuro lament L (KLH).
SpecificityRecognizes human Neuro lament L.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names68kD Neurofilament Protein, Micro Glutamic Acid-Rich Protein


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