Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Neurofilament » Anti -Neurofilament H, 160kD (NF-H)

Anti -Neurofilament H, 160kD (NF-H)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IH
Neurofilaments can be defined as the intermediate or 10 nm filaments found in specifically in neuronal cells. In the electron microscope neurofilaments appear as 10 nm diameter fibres of indeterminate length which generally have fine wispy protrusions from their sides. They are found particularly abundantly in axons of large projection neurons. They probably function to provide structural support for neurons and their synapses and to support the large axon diameters required for rapid conduction of impulses down axons. They are composed a mixture of subunits which usually include the three neurofilament triplet proteins known as NFL, NFM and NFH. Neurofilaments may also include smaller amounts of peripherin, alpha internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable.
Catalog #N2160-04D
Application(s) Immunohistochemistry
Recommended DilutionImmunohistochemistry: 510ug/ml
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q191
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified immunoglobulin
ImmunogenPurified neurofilament polypeptides.
SpecificityReacts with neurofilament 160kD (1, 2).
Species ReactivityHuman, porcine, rat and other higher invertebrates.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


External Links