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Abs to Neurofilament
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Anti -Neurofilament, heavy chain, 180-220kD (NF-H)
Anti -Neurofilament, heavy chain, 180-220kD (NF-H)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B IH IF |
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| Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-L antibody can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig’s disease or Alzheimerís disease. | | | Catalog # | N2160-06L | | Application(s) | Immunohistochemistry, Western Blot. | | Recommended Dilution | Western Blot 1:5000 | | Immunohistochemistry 1:1000. Cryostat sections and formalin-fixed paraffin-embedded sections | | Immunofluorescence (1:1,000) | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Rat | | Concentration | Not determined | | Form | Supplied as serum, 0.1% sodium azide. | | Purity | Serum | | Immunogen | Recombinant C terminal extension of rat NF-H | | Specificity | Recognizes both phosphorylated and non-phosphorylated forms of NF-H. Specifically recognizes the heavy microfilament subunit (~180-220kD). Species crossreactivity: Human, feline, rat, bovine, mouse and porcine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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