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You are here:Home » Antibodies » Abs to Neurofilament » Anti -Neurofilament H, 200kD (NF-H, NFH, 200kD Neurofilament Protein, KIAA0845, NEFH, Neurofilament Heavy Polypeptide 200kD, Neurofilament Heavy Polypeptide, Neurofilament Triplet H Protein, NF200)

Anti -Neurofilament H, 200kD (NF-H, NFH, 200kD Neurofilament Protein, KIAA0845, NEFH,
Neurofilament Heavy Polypeptide 200kD, Neurofilament Heavy Polypeptide, Neurofilament
Triplet H Protein, NF200)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Serum B IF
Neurofilaments can be defined as the intermediate or 10nm filaments found specifically in neuronal cells. Neurofilaments appears as fibres of indeterminate length which generally have fine wispy protrusions from their sides. They are found abundantly in axons of large projection neurons. They probably function to provide structural support for neurons and their synapses and to support the large axon diameters required for rapid axon impulse conduction. They are composed of a mixture of subunits which usually include the three neurofilament triplet proteins, known as NF-L, NF-M and NF-H. Neurofilaments may also include smaller amounts of peripherin, a-internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons, and are biochemically very stable.
Catalog #N2160-06T
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50%glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceBovine
ConcentrationNot determined
FormAs reported
PuritySerum
ImmunogenPurified by NF-H protein from Bovine intermediate filaments prepared from spinal cords.
SpecificityRecognizes bovine Neurofilament H. Species Crossreactivity: Human, mouse, rat, and cat. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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