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Abs to Neurofilament
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Anti -NF-H (Neurofilament heavy polypeptide, Neurofilament triplet H protein, 200kD, NEFH, KIAA0845, NFH)
Anti -NF-H (Neurofilament heavy polypeptide, Neurofilament triplet H protein, 200kD, NEFH, KIAA0845, NFH)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| Neurofilaments contain three intermediate filament proteins: L, M and H, which are involved in the maintenance of the neuronal caliber. NF-H has an important function in mature axons. NF-H is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Defects in NF-H are a cause of amyotrophic lateral sclerosis (ALS) which is a neurodegenerative disorder affecting upper and lower motor neurons and results in fatal paralysis. | | | Catalog # | N2160-12A | | Applications | Suitable for use in Western Blot and ELISA. Other applications have not been tested. | | Recommended Dilutions | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9G402 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O. | | Purity | Purified by affinity chromatography. | | Immunogen | Partial recombinant human NF-H protein (263-364) with a GST tag. | | Specificity | Recognizes human NF-H. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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