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You are here:Home » Antibodies » Abs to Neurofilament » Anti -NF-H (Neurofilament heavy polypeptide, Neurofilament triplet H protein, 200kD, NEFH, KIAA0845, NFH)

Anti -NF-H (Neurofilament heavy polypeptide, Neurofilament triplet H protein, 200kD, NEFH,
KIAA0845, NFH)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Neurofilaments contain three intermediate filament proteins: L, M and H, which are involved in the maintenance of the neuronal caliber. NF-H has an important function in mature axons. NF-H is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Defects in NF-H are a cause of amyotrophic lateral sclerosis (ALS) which is a neurodegenerative disorder affecting upper and lower motor neurons and results in fatal paralysis.
Catalog #N2160-12A
ApplicationsSuitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G402
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant human NF-H protein (263-364) with a GST tag.
SpecificityRecognizes human NF-H.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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