NFKBIA, Recombinant, Human, aa1-317, His-tag (NF-kappa-B Inhibitor alpha, I-kappa-B-alpha,
IkappaBalpha, IkB-alpha, Major Histocompatibility Complex Enhancer-binding Protein MAD3,
NFKBI, MAD3, IKBA)
Pricing
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| NF-kappa-B inhibitor alpha, also known as NFKBIA, is members of the IkB family of proteins can be divided into four groups (IkB-alpha, IkB-beta, IkB-gamma, IkB-epsilon). NFKBIA inhibits the NFkB complex by binding and sequestering it in the cytoplasm. Upon stimulation, NFKBIA is phosphorylated on serine residues marking it for degradation by the ubiquitin pathway. | | | Catalog # | N2306-61A | | Source | Recombinant corresponding to aa1-317 from human NFKBIA, fused to His-tag at N-terminal expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MFQAAERPQE WAMEGPRDGL KKERLLDDRH DSGLDSMKDE EYEQMVKELQ EIRLEPQEVP RGSEPWKQQL TEDGDSFLHL AIIHEEKALT MEVIRQVKGD LAFLNFQNNL QQTPLHLAVI TNQPEIAEAL LGAGCDPELR DFRGNTPLHL ACEQGCLASV | | GVLTQSCTTP HLHSILKATN YNGHTCLHLA SIHGYLGIVE LLVSLGADVN AQEPCNGRTA LHLAVDLQNP DLVSLLLKCG ADVNRVTYQG YSPYQLTWGR PSTRIQQQLG QLTLENLQML PESEDEESYD TESEFTEFTE DELPYDDCVF GGQRLTL | | Molecular Weight | ~37.7kD (MALDI-TOF) | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~37.7kD | | Source | E.coli | | Purity | ~90% (SDS-PAGE) | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 20% glycerol, 0.1M sodium chloride | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for NFKBIA, Recombinant, Human, aa1-317, His-tag (NF-kappa-B Inhibitor alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, Major Histocompatibility Complex Enhancer-binding Protein MAD3, NFKBI, MAD3, IKBA) |
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