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You are here:Home » Biochemicals » Biochem-Nicotine Derivatives » (2'S)-Nicotine 1-Oxide

(2'S)-Nicotine 1-Oxide


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Nicotine-1-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
Catalog #N2561-90Z
AtmosphereInert gas
SolubilityChloroform, Methanol
Storage and StabilityStore at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number2820-55-5
Molecular FormulaC10H14N2O
Molecular Weight178.19
FormLight orange, low-melting solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards All products should be handled by qualified personnel only, trained in laboratory procedures.

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