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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -Nicotinic Acetylcholine Receptor alpha 1 (nAChR, Acetylcholine Receptor Protein alpha Chain Precursor, ACHRA, ACHRD, Cholinergic Receptor Nicotinic alpha Polypeptide 1, CHRNA1, CHNRA, CMS2A, FCCMS, SCCMS, Schizophrenia Neurophysiologic Defect Candidate)

Anti -Nicotinic Acetylcholine Receptor alpha 1 (nAChR, Acetylcholine Receptor Protein
alpha Chain Precursor, ACHRA, ACHRD, Cholinergic Receptor Nicotinic alpha Polypeptide 1,
CHRNA1, CHNRA, CMS2A, FCCMS, SCCMS, Schizophrenia Neurophysiologic Defect Candidate)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subunit gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.
Catalog #N2562-08F
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.75ug/ml
Immunohistochemistry (paraffin): 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with sterile dH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a sequence at the N-terminal of human CHRNA1, identical to the related rat and mouse sequence.
SpecificityRecognizes human CHRNA1. Species Cross-Reactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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