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You are here:Home » Antibodies » Antibodies-Membrane Proteins » Anti -Nidogen (Entactin) G2

Anti -Nidogen (Entactin) G2


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Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B
The extracellular matrix is a complex network of secreted (glyco)proteins situated in between cells of particular types of tissue. The relative amounts of the different types of matrix macromolecules and the way in which they are organized in the extracellular matrix vary between different tissues. For example, connective tissues have extensive extracellular matrices in which fibrous polymers, especially collagen, are present. In contrast, in epithelial tissues the extracellular matrix consists only of a thin mat called the basal lamina, which underlies the epithelial cell sheet. Cells located in the extracellular matrix produce matrix constituents and control the organization of these matrix components. The main components of the extracellular matrix are proteoglycans (e.g. aggrecan, perlecan and syndecan) and fibrous proteins (e.g. collagen, elastin, fibronectin and laminin). The extracellular matrix, next to being a scaffold to support cells in a particular tissue, also plays a role in the regulation of processes such as proliferation, differentiation, adhesion and locomotion of these cells.
Catalog #N2566-10
ApplicationsWestern blot: Recognizes native and denatured nidogen.
This antibody is able to block the binding of nidogen to laminin.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No2Q580
FormSupplied as a liquid in PBS, pH 7.5, 0.1% sodium azide.
ImmunogenRecombinant fragment corresponding to the G2 region of mouse nidogen
SpecificityRecognizes G2 region of mouse nidogen. Species Crossreactivity: Human
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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