Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Calcium Binding Proteins » Anti -NIR2 (NIR-2, DRES9, Drosophila Retinal Degeneration B, Phosphatidylinositol Transfer Protein Membrane-associated, PITPNM, PYK2 N-terminal Domain-interacting Receptor 2, RD9, RDGB, RDGB1, RDGBA1)

Anti -NIR2 (NIR-2, DRES9, Drosophila Retinal Degeneration B, Phosphatidylinositol Transfer
Protein Membrane-associated, PITPNM, PYK2 N-terminal Domain-interacting Receptor 2, RD9,
RDGB, RDGB1, RDGBA1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
NIR2 belongs to a family of proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis.
A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking and distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.
Catalog #N2568-42
Cellular Localization Cytoplasmic
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: KARSISLKLDSEE, representing the C-terminus of the human protein (residues 1232-1244) according to NP_004901.
SpecificitySpecies Crossreactivity: Mouse. Expected to crossreact with Human (100% homology).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links