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Anti -NIR2 (NIR-2, DRES9, Drosophila Retinal Degeneration B, Phosphatidylinositol Transfer Protein Membrane-associated, PITPNM, PYK2 N-terminal Domain-interacting Receptor 2, RD9, RDGB, RDGB1, RDGBA1)
Anti -NIR2 (NIR-2, DRES9, Drosophila Retinal Degeneration B, Phosphatidylinositol Transfer
Protein Membrane-associated, PITPNM, PYK2 N-terminal Domain-interacting Receptor 2, RD9,
RDGB, RDGB1, RDGBA1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| NIR2 belongs to a family of proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis. | | | A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking and distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration. | | | Catalog # | N2568-42 | | Cellular Localization | Cytoplasmic | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: KARSISLKLDSEE, representing the C-terminus of the human protein (residues 1232-1244) according to NP_004901. | | Specificity | Species Crossreactivity: Mouse. Expected to crossreact with Human (100% homology). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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