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You are here:Home » Antibodies » Abs to Tumor Suppressors » Anti -NPRL2 (Nitrogen Permease Regulator 2-like Protein, NPR2-like Protein, Gene 21 Protein, G21 Protein, Tumor Suppressor Candidate 4, TUSC4)

Anti -NPRL2 (Nitrogen Permease Regulator 2-like Protein, NPR2-like Protein, Gene 21
Protein, G21 Protein, Tumor Suppressor Candidate 4, TUSC4)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Catalog #N2592-48C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 1-3ug/ml, observed in human skeletal muscle lysates on ~48kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-TKQGHKRASLRD, from human TUSC4, at the internal region of the protein (NP_006536.3).
SpecificityRecognizes human TUSC4. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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