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Anti -NPRL2 (Nitrogen Permease Regulator 2-like Protein, NPR2-like Protein, Gene 21 Protein, G21 Protein, Tumor Suppressor Candidate 4, TUSC4)
Anti -NPRL2 (Nitrogen Permease Regulator 2-like Protein, NPR2-like Protein, Gene 21
Protein, G21 Protein, Tumor Suppressor Candidate 4, TUSC4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs. | | | Catalog # | N2592-48D | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:32,000 | | Western Blot: 0.1-0.3ug/ml, observed in Human Skeletal Muscle lysates on ~45kD bands | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to QYSNVYCPTPKV, from human TUSC4, at the internal region of the protein (NP_006536.3). | | Specificity | Recognizes human TUSC4. Species sequence homology: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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