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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -NKX3.1 (Homeobox Protein Nkx-3.1, Homeobox Protein NK-3 Homolog A, NKX3-1, NKX3A)

Anti -NKX3.1 (Homeobox Protein Nkx-3.1, Homeobox Protein NK-3 Homolog A, NKX3-1, NKX3A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and tumorigenesis. NKX3.1 expression is dramatically down-regulated in testicular cancer of germ cell origin. Results suggest that NKX3.1 is essential for normal testis function and that its loss of expression is highly associated with the invasive phenotype of testicular germ cell tumors.
Catalog #N2850-30E
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:5000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa21-37 [TPSKPLTSFLIQDILRD] of human NKX3.1.
SpecificityRecognizes human NKX3.1. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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