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Anti -NMDA 1 Receptor, CT, C2 Cassette (NMDA R1, N-methyl-D-aspartate)
Anti -NMDA 1 Receptor, CT, C2 Cassette (NMDA R1, N-methyl-D-aspartate)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IH |
|
| The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy- 5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism. | | | Catalog # | N2904-15 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Western Blot: 1:100-1:500 | | Immunohistochemistry: 1:100-1:500. Using paraformaldehyde or paraformaldehyde/glutaraldehyde fixed tissue with light and electron microscopy. | | Optimal dilution determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 2Q155 | | Host | Mouse | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% sodium azide. | | Purity | Purified | | Immunogen | Synthetic peptide corresponding to LQNQKDTVLPRRAIEREEGQLQLCSRHRES from the C-terminus of rat NMDA receptor subunit. | | Specificity | Recognizes rat NMDAR1, C-terminal, C2 cassette. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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