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You are here:Home » Antibodies » Abs to Ion Channel » Anti -NMDA 1 Receptor, CT, C2 Cassette (NMDA R1, N-methyl-D-aspartate)

Anti -NMDA 1 Receptor, CT, C2 Cassette (NMDA R1, N-methyl-D-aspartate)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IH
The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy- 5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.
Catalog #N2904-15
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:100-1:500
Immunohistochemistry: 1:100-1:500. Using paraformaldehyde or paraformaldehyde/glutaraldehyde fixed tissue with light and electron microscopy.
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No2Q155
HostMouse
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to LQNQKDTVLPRRAIEREEGQLQLCSRHRES from the C-terminus of rat NMDA receptor subunit.
SpecificityRecognizes rat NMDAR1, C-terminal, C2 cassette.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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