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Specifications

Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram +ve activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and acts as a competitive inhibitor of the ATPase reaction catalysed by GyrB.
Catalog #	N5376-61
Source	Novobiocin from Stretomyces sp.
Molecular Weight	~612.6
Solubility	Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	303-81-1
Molecular Formula	C31H36N2O11
Molecular Weight	~612.6
Purity	~95% (HPLC)
Concentration	Not determined
Form	Supplied as a pale yellow solid.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.