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You are here:Home » Antibodies » Abs to Defensin » Anti -Neutrophil Defensin 1, 3 (Defensin, alpha 1, HNP-1, HP-1, HP1, DEFA1, DEF1, DEFA2, MRS, DEFA1B/Defensin, alpha 3, HNP-3, HP-3, HP3, DEFA3, DEF3)

Anti -Neutrophil Defensin 1, 3 (Defensin, alpha 1, HNP-1, HP-1, HP1, DEFA1, DEF1, DEFA2,
MRS, DEFA1B/Defensin, alpha 3, HNP-3, HP-3, HP3, DEFA3, DEF3)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Defensin alpha 1, otherwise known as HNP-1, is a secreted cationic antimicrobial peptide and member of the alpha-defensin family, which plays an important role in the innate immune response against microbial infections.
Catalog #N5377-03P
Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Western Blot: 1-3ug/ml
Immunohistochemistry (Paraffin): 4-6ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DESLAPKHPGSRKN, from human DEFA1,3, at the internal region of the protein (NP_004075.1, NP_005208.1).
SpecificityRecognizes human DEFA1,3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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