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You are here:Home » Antibodies » Abs to Nuclear Proteins » Anti -NUP98 (ADIR2, Nuclear pore complex protein Nup98-Nup96 precursor, NUP196)

Anti -NUP98 (ADIR2, Nuclear pore complex protein Nup98-Nup96 precursor, NUP196)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit B IP IF
NUP98 (nucleoporin 98kD) is a component of the nuclear pore complex. It is expressed as three different precursors that undergo auto-cleavage to generate a common amino-terminal 98kD peptide (NUP98) and carboxy-terminal 6, 96 (NUP96) and 88 (p88)kD peptides (1-2). NUP98 contains FG and GLFG repeat domains at its amino terminus and a RNA-binding domain in its carboxy terminus (3). The NUP98 gene is localized on chromosome 11p15.5, a region frequently rearranged in leukemias. To date, 15 fusion partners have been identified for NUP98 (4-5).
Catalog #N5378-61
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:50
Western Blot: 1:1000
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No8A21
HostRabbit
SourceHuman
FormSupplied as a liquid in 10mM sodium HEPES (pH 7.5), 150 mM NaCl, 100ug/ml BSA, 50% glycerol and less than 0.02% sodium azide.
PurityAs reported
ImmunogenSynthetic peptide (KLH-coupled) corresponding to residues surrounding Pro671 of human NUP98.
SpecificityDetects endogenous levels of total NUP98 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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