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Anti -NUP98 (ADIR2, Nuclear pore complex protein Nup98-Nup96 precursor, NUP196)
Anti -NUP98 (ADIR2, Nuclear pore complex protein Nup98-Nup96 precursor, NUP196)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
|
B IP |
|
| NUP98 (nucleoporin 98kD) is a component of the nuclear pore complex. It is expressed as 3 different precursors which undergo auto-cleavage to generate a common amino-terminal 98kD peptide (NUP98) and carboxy-terminal 6, 96 (NUP96) and 88 (p88)kD peptides, respectively (1-2). NUP98 contains FG and GLFG repeat domains at its amino terminus and a RNA-binding domain in its carboxy terminus (3). The NUP98 gene is localized on chromosome 11p15.5, a region frequently rearranged in leukemias. To date, 15 fusion partners have been identified for NUP98 (4-5). | | | Catalog # | N5378-61A | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 | | Immunoprecipitation: 1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 8A22 | | Host | Rabbit | | Source | Human | | Form | Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/mlBSA, 50% glycerol, 0.02% sodium azide. | | Purity | As reported | | Immunogen | Synthetic peptide (KLH-coupled) corresponding to residues surrounding Leu518 of human NUP98. | | Specificity | Detects endogenous levels of total NUP98. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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