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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -NRAS (Neuroblastoma RAS Viral (v-ras) Oncogene Homolog, N-Ras, ALPS4, AV095280, GTPase NRas, HRAS1, N-Ras Protein Part 4, NRAS1, OTTHUMP00000013879, OTTMUSP00000023521, Transforming Protein N-Ras, v-Ras Neuroblastoma RAS Viral Oncogene Homolog)

Anti -NRAS (Neuroblastoma RAS Viral (v-ras) Oncogene Homolog, N-Ras, ALPS4, AV095280,
GTPase NRas, HRAS1, N-Ras Protein Part 4, NRAS1, OTTHUMP00000013879, OTTMUSP00000023521,
Transforming Protein N-Ras, v-Ras Neuroblastoma RAS Viral Oncogene Homolog)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML).
Catalog #N5385-01A
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other Applications not tested.
Recommended DilutionsELISA: 1:32,000
Western Blot: 0.01-0.03ug/ml
Immunohistochemistry (Paraffin): 2-3ug/ml Requires HEIR using citrate buffer pH6.0
Optimal dilutions to be determined by the researcher.
Positive ControlHuman lysates of cell line A431
Blocking PeptideN5385-01A1
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 monthsat -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide, C-RMKKLNSSDDGTQ, from the internal region of human NRAS.
SpecificityRecognizes human NRAS at ~21kD. Species sequence homology: mouse, rat, canine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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