Anti -NRAS (Neuroblastoma RAS Viral (v-ras) Oncogene Homolog, N-Ras, ALPS4, AV095280,
GTPase NRas, HRAS1, N-Ras Protein Part 4, NRAS1, OTTHUMP00000013879, OTTMUSP00000023521,
Transforming Protein N-Ras, v-Ras Neuroblastoma RAS Viral Oncogene Homolog)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
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| This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). | | | Catalog # | N5385-01A | | Applications | Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other Applications not tested. | | Recommended Dilutions | ELISA: 1:32,000 | | Western Blot: 0.01-0.03ug/ml | | Immunohistochemistry (Paraffin): 2-3ug/ml Requires HEIR using citrate buffer pH6.0 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human lysates of cell line A431 | | Blocking Peptide | N5385-01A1 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 monthsat -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide, C-RMKKLNSSDDGTQ, from the internal region of human NRAS. | | Specificity | Recognizes human NRAS at ~21kD. Species sequence homology: mouse, rat, canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -NRAS (Neuroblastoma RAS Viral (v-ras) Oncogene Homolog, N-Ras, ALPS4, AV095280, GTPase NRas, HRAS1, N-Ras Protein Part 4, NRAS1, OTTHUMP00000013879, OTTMUSP00000023521, Transforming Protein N-Ras, v-Ras Neuroblastoma RAS Viral Oncogene Homolog) |
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