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You are here:Home » Antibodies » Abs to Neurotrophins » Anti -NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2)

Anti -NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
NT-3 is a neurotrophic factor structurally related to NGF, BDNF and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6kD polypeptide monomers (238 total amino acid residues).
Catalog #N6000-07B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No1.A.23
HostMouse
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in 0.1M Tris HCl, pH 7.5.
PurityPurified by Protein G affinity chromatography.
ImmunogenPuri ed human recombinant NT-3 protein expressed in CHO cells.
SpecificityRecognizes recombinant human NT-3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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