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Anti -NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2)
Anti -NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| NT-3 is a neurotrophic factor structurally related to NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6kD polypeptide monomers (238 total amino acid residues). | | | Catalog # | N6000-07E | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-2ug/ml | | Immunohistochemistry: 0.5-2ug/ml | | Optimal dilutions to be determined by the researcher. | | Reconstitution | Desired volume with sterile distilled water. | | Suggested concentration | 0.5–1mg/mL. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~0.5-1mg/ml | | Form | Supplied as a lyophilized powder in PBS. No preservatives added. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | An 11 amino acid peptide corresponding to the amino-terminal of mouse Neurotrophin 3 (NT3) coupled to BSA. | | Specificity | Recognizes Neurotrophin 3 (NT3). Does not crossreact with BDNF or NGF. Species Reactivity: Human, rat, chicken. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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