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You are here:Home » Antibodies » Abs to RNA Binding Proteins » Anti -NUFIP2 (Nuclear Fragile X Mental Retardation Protein Interacting Protein 2, 182-FIP, 82-FIP, 82kD FMRP-interacting Protein, Cell Proliferation-inducing Gene 1 Protein, FIP-82, FLJ10976, FMRP-interacting Protein 2, KIAA1321, MGC117262, Nuclear Fragile X Me

Anti -NUFIP2 (Nuclear Fragile X Mental Retardation Protein Interacting Protein 2, 182-FIP,
82-FIP, 82kD FMRP-interacting Protein, Cell Proliferation-inducing Gene 1 Protein, FIP-82,
FLJ10976, FMRP-interacting Protein 2, KIAA1321, MGC117262, Nuclear Fragile X Me

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
82kD FMRP Interacting Protein is a novel FMRP-interacting protein associated to polyribosomes as a component of mRNP complexes containing FMRP. FMRP is an RNA binding protein whose absence produces pathological manifestations of the fragile-X syndrome. 82kD FMRP Interacting Protein is found in both nucleus and cytoplasm in some neurons, while it appears only cytoplasmic in others. Subcellular distribution of the protein is cell cycle-dependent in cultured cells. The protein plays a significant role in the development of the nervous system and in cognitive function. Mutation and defect in the protein might be implicated in forms of mental retardation or cognitive impairment. The gene encoding for human 82kD FMRP Interacting Protein is localized on chromosomal region 17q11.2.
Catalog #N6878-50
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa676-695 (QKQDPKRIITYNEAMDSPDQ) of human 82kD FMRP Interacting.
SpecificityRecognizes human 82kD FMRP Interacting Protein. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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