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You are here:Home » Antibodies » Abs to Nuclear Proteins » Anti -Nucleolar Protein Family A, Member 1 (GAR1 Protein, NOLA1)

Anti -Nucleolar Protein Family A, Member 1 (GAR1 Protein, NOLA1)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified E B
The gene that encodes this protein is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p.
Catalog #N6939-61
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-217
Protein GI Number15011916
Protein Accession #NP_127460.1
SpecificityRecognizes human Nucleolar Protein Family A, Member 1.
Species CrossreactivityHuman, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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