Anti -NUP210 (Nuclear Pore Membrane Glycoprotein 210, Nuclear Pore Protein gp210, Nuclear
Envelope Pore Membrane Protein POM 210, POM210, Nucleoporin Nup210, Pore Membrane Protein
of 210kD, KIAA0906, PSEC0245)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E |
|
| NUP210 is a regulatory protein with 1887aa and functions as a nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. This structural protein generally forms dimers and possibly higher-order oligomers and belongs to the NUP210 family. Ubiquitous expression is seen in most of the tissues with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. Knockdown of NUP210 causes nuclear membranes to accumulate aberrant structures termed twinned and fusion-arrested membranes and nuclear pore complex to cluster and may induce cell death and chromatin disruptions. | | | Catalog # | N7100-56A | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:100-1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.025% sodium azide, 50% glycerol. | | Purity | Serum. | | Immunogen | Synthetic peptide corresponding to aa284-299 QLQNSIPGPEGDPARP of human NUP210. | | Specificity | Recognizes human NUP210. Species sequence homology: canine, mouse, opossum, rat, rhesus monkey. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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