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You are here:Home » Molecular Biology » MB-Enzymes, Phosphatase » NUDT5, aa1-219, Recombinant, Human (ADP-sugar Pyrophosphatase, HSPC115, hYSAH1, Nucleoside Diphosphate-linked Moiety X Motif 5, Nudix Motif 5, YSA1H)

NUDT5, aa1-219, Recombinant, Human (ADP-sugar Pyrophosphatase, HSPC115, hYSAH1, Nucleoside
Diphosphate-linked Moiety X Motif 5, Nudix Motif 5, YSA1H)

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Specifications

NUDT5 is a member of the nudix hydrolase family which eliminate toxic nucleotide derivatives from the cell. NUDT5 hydrolyzes ADP-ribose and ADP-mannose in the presence of magnesium, and also hydrolyzes other nucleotide sugars with low activity such as ADP-glucose and diadenosine diphosphate. As a nudix hydrolase, NUDT5 contains a central nudix motif and functions to eliminate toxic nucleotide metabolites from the cell while maintaining the levels of signaling nucleotides. NUDT5 is widely expressed but is most abundant in liver as a homodimer.
Catalog #N7400-22
SourceRecombinant corresponding to aa1-219 of human NUDT5 6x his tagged, expressed in E.coli.
AA SequenceMGSSHHHHHH SSGLVPRGSH MESQEPTESS QNGKQYIISE ELISEGKWVK LEKTTYMDPT GKTRTWESVK RTTRKEQTAD GVAVIPVLQR TLHYECIVLV KQFRPPMGGY CIEFPAGLID DGETPEAAAL RELEEETGYK GDIAECSPAV CMDPGLSNCT IHIVTVTING DDAENARPKP KPGDGEFVEV ISLPKNDLLQ RLDALVAEEH LTVDARVYSY ALALKHANAK PFEVPFLKF
Molecular Weight 26.5kD (239aa), confirmed by MALDI-TOF
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight26.5kD
SourceE.coli
Purity~85% (SDS-PAGE).
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol, 1mM DTT, 0.1M sodium chloride.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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