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You are here:Home » Molecular Biology » MB-Protein Kinase Inhibitors » NVP-BEZ235 (4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-alpha,alpha-dimethyl-benzeneacetonitrile, BEZ235)

NVP-BEZ235
(4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-alpha,alph
a-dimethyl-benzeneacetonitrile, BEZ235)

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Specifications

Orally active PI-3 kinase inhibitor; Dual PI3K/mTOR inhibition, BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer.
Catalog #N8569-60A
SolubilityDMSO (10mM)
Molecular Weight~469.55
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number915019-65-7
Molecular FormulaC H N O
Molecular Weight469.55
Purity~99% (HPLC)
FormSupplied as an off-white to pale yellow solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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