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NVP-BEZ235 (4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-alpha,alpha-dimethyl-benzeneacetonitrile, BEZ235)
NVP-BEZ235
(4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-alpha,alph
a-dimethyl-benzeneacetonitrile, BEZ235)
Pricing
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| Orally active PI-3 kinase inhibitor; Dual PI3K/mTOR inhibition, BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer. | | | Catalog # | N8569-60A | | Solubility | DMSO (10mM) | | Molecular Weight | ~469.55 | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 915019-65-7 | | Molecular Formula | C H N O | | Molecular Weight | 469.55 | | Purity | ~99% (HPLC) | | Form | Supplied as an off-white to pale yellow solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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