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NXT1, Recombinant, Human (NTF2-related Export Protein 1, NTF2-like Export Factor 1)
NXT1, Recombinant, Human (NTF2-related Export Protein 1, NTF2-like Export Factor 1)
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| This protein is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. | | | Catalog # | N8570 | | Species | Homo sapiens | | Source | E. coli | | Primary Sequence (aa) | 140 | | Domain (aa) | Full-length | | Tag/Fusion Partner | T7 Tag | | Applications | Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Other applications not tested. | | Quality Control | SDS-PAGE Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | Important note | This recombinant enzyme has NOT been tested with regard to biological activity. | | Source | E. coli | | Purity | Highly purified | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2. No preservative added. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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