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You are here:Home » Antibodies » Abs to Nuclear Proteins » Anti -NTF2 (NTF-2, Nuclear transport factor 2, NUTF2)

Anti -NTF2 (NTF-2, Nuclear transport factor 2, NUTF2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP IC N
NTF2-related export protein 1 is a protein that in humans is encoded by the NXT1 gene. The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor . This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance) -dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
Catalog #N8570-02
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry and Neutralization. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml detects a band at 14kD
Immunocytochemistry: fixation with 3.7% formaldehyde-0.2% Triton X-100 or 4% paraformaldehyde-methanol.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No9A62
HostMouse
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
PurityPurified by affinity chromatography.
ImmunogenRecombinant full length human NFT2. Epitope
SpecificityRecognizes human NXT1. Species Crossreactivity: mouse, rat, Xenopus laevis, chicken, monkey, hamster.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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